(Please make sure you have read and understand our pain medication policy and payment policy before you place an order or reorder.)

Tramacet is an effective pain relief medication which can be used to treat cases of moderate to severe pain, commonly caused by chronic conditions such as rheumatoid arthritis. It is a combination medication containing both tramadol hydrochloride and paracetamol, designed to provide relief in cases where milder pain relievers prove insufficient.

If you are suffering with chronic pain, you can buy Tramacet online from Express Doctor. Our consultation service is secure and easy to use.

ATTENTION: Please note that the monthly limitations are per household per month.

Tramacet (Zaldiar) 325mg/37.5mg60 Tablets£4656.57 €

Please be aware that this medicationcontains tramadol hydrochloride which is a very strong pain medicating agent. You can only buy Tramacet with a valid prescription, and it should only be taken under the supervision of a qualified healthcare professional. It should not be used by patients who: are pregnant; have ever suffered from severe depression, alcohol or drug dependency; are currently taking other medication such as valium, tranquilisers, antipsychotics or narcotics; are already taking paracetamol in another form; or who are susceptible to seizures, metabolic disorders or kidney disease. Disclose your full medical history to your prescriber before purchase and use.

Side effects may include: constipation, nausea and vomiting, increased perspiration or withdrawal, leading to muscular contractions. Patients should also avoid driving and operating heavy machinery while taking this medication. The information provided here is not comprehensive. For a full list of side effects, restrictions and safety information, consult the leaflet provided or ask your prescriber. If you become unwell or display signs of an allergic reaction while using this treatment, seek medical advice immediately.

What is included in the price shown on the website?


No Prescription Required

You will be presented with a medical questionnaire written by our doctor. The price you pay includes a UK registered doctor to review your answers and issue you a valid prescription.

Prescription Processing

Once your order has been approved by our doctor, your prescription will be forwarded to a UK registered pharmacy responsible for dispensing your medication. To view one of our partner pharmacies’ registration details click here.

Discreet Secure Packaging

A UK registered pharmacy will dispense your medicines and place them in secure plain packaging. All medicines are sealed in tamper proof secure bags.

24 Hour Next Day delivery – Fully Tracked Secure Delivery

Our partner pharmacies only use fully tracked couriers. In most cases your medicines will be sent using TNT. You will be sent a tracking number once the pharmacy has shipped your medicine so you can track the parcel whilst its on its way to you. All medicines are sent via a ‘guaranteed next day delivery’ service.

Same Day Despatch For 24 Hour Delivery

If your order has been approved by our doctor by 3pm (GMT/UK time), then this order will be dispensed by our partner pharmacy on the same day and you will receive your medicines the next working day. Please note that TNT do not deliver on weekends. All deliveries will require a signature, therefore if you are aware of not being home the next day, please provide an alternative delivery address when placing your order.

Dedicated Customer Service

We are here to help! If your require any further information or help in ordering, please do not hesitate to contact us on 0203 239 8452 or you can email us on

Important Information


  • Recommendation of 1-2tablets every 4-6hours
  • Can be ingested with a full or empty stomach


  • Tablet in 37.5mg/325 mg preparations (37.5 mg Tramadol and 325 mg Acetaminophen)


  • Avoid taking Tramacet with other Acetaminophen drugs like Tylenol
  • Avoid taking with antidepressants, anti-psychotics, and tranquilizers
  • Those with kidney and liver problems should not take Tramacet
  • Driving and machine operation is not recommended as this can affect one’s mental status and alertness
  • Not advisable to take by pregnant women and children


  • Nausea and vomiting
  • Constipation
  • Withdrawal symptoms like tremors, trembling hands, and muscle contractures
  • Headache
  • Sleepiness/dizziness
  • Respiratory depression
  • Allergic reactions